1、教育经历
(1) 2001/09 – 2004/06,兰州大学,有机化学,博士,导师:涂永强 院士
(2) 1998/09 – 2001/06,兰州大学,有机化学,硕士,导师:陈耀祖 院士
(3) 1994/09 – 1998/06,兰州大学,有机化学,学士,国家级化学专业基地班
2、工作经历
(1) 2024/03 – 至今,中国药科大学,药学院药物化学系,教授、博士生导师
(2) 2008/09 – 2024/02,华东理工大学,化学与分子工程学院,副教授、教授、博士生导师
(3) 2004/12 – 2008/08,香港科技大学化学系和香港理工大学应用生物与化学科技系,博士后
3、学术荣誉
国家杰出青年基金获得者(2019)
中国高被引学者
上海高校“东方学者”特聘教授(2015)及其跟踪计划(2018)
教育部新世纪优秀人才支持计划(2013年)
上海市“浦江人才”计划(2009年)
(1) 肿瘤靶点相关的小分子药物设计、合成与作用机理解析
(2) 医用高分子的设计合成与药物分子的靶向递送
(3) 低维有机纳米材料的表面合成与性质研究
课题组网页:
https://www.x-mol.com/groups/liu_pn1
已发表SCI论文120余篇,其中作为PI独立工作后从2010年至今以通讯作者发表中科院一、二区SCI论文80余篇,包括Acc. Chem. Res.、J. Am. Chem. Soc.(11篇)、Angew. Chem. Int. Ed.(5篇)、Nat. Commun.(2篇)、Adv. Mater.等。已主持国家自然科学基金项目8项和省部级项目8项,参与国家自然科学基金重大项目1项和创新研究群体项目1项。
近五年代表作:
1.X. Li,* M.-L. Gao, S.-S. Wang, Y.-L. Li, T.-N. Liu, H. Xiang,* P.-N. Liu*, Engineering an Organic Nanoplatform for Augmented Pyroeletroimmunotherapy, Adv. Mater. 2024, 36, 2400756.
2.Y. Wang, W.-W. Gong, Y. Zhao, G.-Y. Xing, L.-X. Kang, F. Sha, Z.-Y. Huang, J.-W. Liu, Y.-J. Han, P. Li, D.-Y. Li,* P.-N. Liu*. Two-Dimensional Nonbenzenoid Heteroacene Crystals Synthesized via In-Situ Embedding of Ladder Bipyrazinylenes on Au(111). Angew. Chem. Int. Ed. 2024, 63, e202318142
3.J.-W. Liu, Y. Wang, L.-X. Kang, Y. Zhao, G.-Y. Xing, Z.-Y. Huang, Y.-C. Zhu, D.-Y. Li*, P.-N. Liu*. Two-Dimensional Crystal Transition from Radialene to Cumulene on Ag(111) via Retro-[2+1] Cycloaddition. J. Am. Chem. Soc. 2023, 145, 13048.
4.G. Zhu, Y. Jiang, Y. Wang, B.-X. Wang, Y. Zheng, Y. Liu, L.-X. Kang, Z. Li, D. Guan, Y. Li, H. Zheng, C. Liu, J. Jia, T. Lin, P.-N. Liu*, D.-Y. Li*, S. Wang*. Collective Quantum Magnetism in Nitrogen-Doped Nanographenes, J. Am. Chem. Soc. 2023. 145, 7136.
5.D.-Y. Li,* Y. Wang, X.-Y. Hou, Y.-T. Ren, L.-X. Kang, F.-H. Xue, Y.-C. Zhu, J.-W. Liu, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. On-Surface Synthesis of [3]Radialenes via [1+1+1] Cycloaddition”. Angew. Chem. Int. Ed. 2022, 61, e202117714.
6.D.-Y. Li, X. Qiu, S.-W. Li, Y.-T. Ren, Y.-C. Zhu, C.-H. Shu, X.-Y. Hou, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. Ladder Phenylenes Synthesized on Au(111) Surface via Selective [2+2] Cycloaddition, J. Am. Chem. Soc. 2021, 143, 12955.
7.D.-Y. Li, Y.-C. Zhu, S.-W. Li, C.-H. Shu, P.-N. Liu*. Post-Functionalization of Supramolecular Polymers on Surface and the Chiral Assembly-Induced Enantioselective Reaction, Angew. Chem. Int. Ed. 2021, 60, 11370.
8.C.-H. Shu, Y. He, R.-X. Zhang, J.-L. Chen, A. Wang, P.-N. Liu*. Atomic-Scale Visualization of Stepwise Growth Mechanism of Metal-Alkynyl Networks on Surfaces, J. Am. Chem. Soc. 2020, 142, 39, 16579.
9.D.-Y. Li, S.-W. Li, Y.-L. Xie, X. Hua, Y.-T. Long, A. Wang, P.-N. Liu*. On-surface synthesis of planar dendrimers via divergent cross-coupling reaction, Nat. Commun., 2019, 10, 2414.
10.X. Li, X. Ma, Z. Wang, P.-N. Liu*, L. Zhang*. Bifunctional Phosphine Ligand Enabled Gold‐Catalyzed Alkynamide Cycloisomerization: Access to Electron‐Rich 2‐Aminofurans and Their Diels–Alder Adducts, Angew. Chem. Int. Ed., 2019, 58, 17180.
11.X. Li,* M.-L. Gao, S.-S. Wang, Y.-L. Li, T.-N. Liu, H. Xiang,* P.-N. Liu*, Engineering an Organic Nanoplatform for Augmented Pyroeletroimmunotherapy, Adv. Mater. 2024, 36, 2400756.
12.Y. Wang, W.-W. Gong, Y. Zhao, G.-Y. Xing, L.-X. Kang, F. Sha, Z.-Y. Huang, J.-W. Liu, Y.-J. Han, P. Li, D.-Y. Li,* P.-N. Liu*. Two-Dimensional Nonbenzenoid Heteroacene Crystals Synthesized via In-Situ Embedding of Ladder Bipyrazinylenes on Au(111). Angew. Chem. Int. Ed. 2024, 63, e202318142
13.J.-W. Liu, Y. Wang, L.-X. Kang, Y. Zhao, G.-Y. Xing, Z.-Y. Huang, Y.-C. Zhu, D.-Y. Li*, P.-N. Liu*. Two-Dimensional Crystal Transition from Radialene to Cumulene on Ag(111) via Retro-[2+1] Cycloaddition. J. Am. Chem. Soc. 2023, 145, 13048.
14.G. Zhu, Y. Jiang, Y. Wang, B.-X. Wang, Y. Zheng, Y. Liu, L.-X. Kang, Z. Li, D. Guan, Y. Li, H. Zheng, C. Liu, J. Jia, T. Lin, P.-N. Liu*, D.-Y. Li*, S. Wang*. Collective Quantum Magnetism in Nitrogen-Doped Nanographenes, J. Am. Chem. Soc. 2023. 145, 7136.
15.D.-Y. Li,* Y. Wang, X.-Y. Hou, Y.-T. Ren, L.-X. Kang, F.-H. Xue, Y.-C. Zhu, J.-W. Liu, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. On-Surface Synthesis of [3]Radialenes via [1+1+1] Cycloaddition”. Angew. Chem. Int. Ed. 2022, 61, e202117714.
16.D.-Y. Li, X. Qiu, S.-W. Li, Y.-T. Ren, Y.-C. Zhu, C.-H. Shu, X.-Y. Hou, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. Ladder Phenylenes Synthesized on Au(111) Surface via Selective [2+2] Cycloaddition, J. Am. Chem. Soc. 2021, 143, 12955.
17.D.-Y. Li, Y.-C. Zhu, S.-W. Li, C.-H. Shu, P.-N. Liu*. Post-Functionalization of Supramolecular Polymers on Surface and the Chiral Assembly-Induced Enantioselective Reaction, Angew. Chem. Int. Ed. 2021, 60, 11370.
18.C.-H. Shu, Y. He, R.-X. Zhang, J.-L. Chen, A. Wang, P.-N. Liu*. Atomic-Scale Visualization of Stepwise Growth Mechanism of Metal-Alkynyl Networks on Surfaces, J. Am. Chem. Soc. 2020, 142, 39, 16579.
19.D.-Y. Li, S.-W. Li, Y.-L. Xie, X. Hua, Y.-T. Long, A. Wang, P.-N. Liu*. On-surface synthesis of planar dendrimers via divergent cross-coupling reaction, Nat. Commun., 2019, 10, 2414.
20.X. Li, X. Ma, Z. Wang, P.-N. Liu*, L. Zhang*. Bifunctional Phosphine Ligand Enabled Gold‐Catalyzed Alkynamide Cycloisomerization: Access to Electron‐Rich 2‐Aminofurans and Their Diels–Alder Adducts, Angew. Chem. Int. Ed., 2019, 58, 17180.
刘培念 教授
李登远教授(博导,兴药领军学者)
蒋炜 副教授
江露露 博士后
刘家岱博士后
本团队拥有充足事业编制用人指标,长期招聘药物化学(含天然产物全合成)、药剂学(含生物高分子材料)等研究方向教授、副教授、博士后!
学术博士招生专业:药物化学
专业博士招生专业:生物与医药-制药工程
学术硕士招生专业:药物化学、化学(理学院)
专业硕士招生专业:药学-药物合成与工艺优化