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药理学硕士生导师--龚国清

  龚国清 男,1966年8月生。1987年中国药科大学药理专业本科毕业,1990年获药理专业硕士学位,2004年获得药理学博士学位。现任药学院药理教研室副教授,药学医学基础实验中心副主任。

  主要研究方向:生化药理。主要研究创新化合物的抗血栓作用、抗炎作用及其机理。近年来参与完成国家自然基金项目2项,国家科技部新药创制重大专项2项;发表SCI论文10余篇;参与申请的发明专利6项,其中已授权专利2项。

  目前主持国家自然科学基金1项,研究创新药物的抗血栓多靶点作用分子机制;参与国家自然科学基金2项,科技部新药创制重大专项2项。

  联系邮箱:gonggq@hotmail.com,联系电话:13951637796

  近年发表的主要文章:

  1. Shaochi Wang, Peng Dai, Yungen Xu, Qiufang Chen, Qihua Zhu, Guoqing Gong*(通讯作者)Design, Synthesis, and Biological Evaluation of Dabigatran

  Etexilate Mimics, A Novel Class of Thrombin Inhibitors Arch. Pharm. Chem. Life Sci. 2015, 348, 595-605

  2. Mei-Ling Jiang, Zhi-Xian Zhang, Yun-Zhan Li , Xin-Hui Wang, Wei Yan, Guo-Qing Gong*(通讯作者) Antidepressant-like effect of evodiamine on chronic unpredictable mild stress rats Neuroscience Letters 588 (2015) 154-158

  3. Yun Yang , Xinhui Wang , Qihua Zhu , Guoqing Gong *(通讯作者), Danmeng Luo , Aidou Jiang , Liyan Yang ,Yungen Xu , Synthesis and pharmacological evaluation of novel limonin derivatives as anti-inflammatory and analgesic agents with high water solubility Bioorganic & Medicinal Chemistry Letters 24 (2014) 1851-1855

  4. Xinhui Wang, Guoqing Gong*(通讯作者), Wenhui Yang, Yunzhan Li, Meiling Jiang, Linlin Li Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model Environmental Toxicology and Pharmacology 36(2013)288-295

  5. Yun-Zhan Li , Guo-Qing Gong *(通讯作者), Wen-Hui Yang , Xin-Hui Wang , Mei-Ling Jiang , Yi Zhou ,Xiao-Zhi Yang , Yun-Gen Xu , Guang-Wei He Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models Thrombosis Research 131 (2013) 425-435

  6. Yi Zhou, Guoqing Gong*(通讯作者), Wenhui Yang, Yin Wang, Jing Xu, Yungen Xu The cardioprotective effect of TG-6, a newly synthesized compound, on ischemia-reperfusion injury in rats European Journal of Pharmacology 683 (2012) 190-196

  7. Xiao-Zhi Yang , Wen-Hui Yang , Yun-Gen Xu* , Xiao-Juan Diao , Guo-qing Gong**(通讯作者) Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activitys European Journal of Medicinal Chemistry 57 (2012) 21-28

  8. Lu Jin, Xiang-Min Jiang, Ping Du, Jing Xu, Guo-qing Gong**(通讯作者), Qiu-juan Wang, Yun-gen Xu* Synthesis and Na+/H+ exchanger inhibitory activityof benzoylguanidine derivatives. European Journal of Medicinal Chemistry,2011,46:4107-4116

  参加编写的专著:

  Evidence-based Anticancer Materia Medica (ISBN 978-94-007-0525-8) (Chapter 9 An Evidence-based perspective of Hedyotis Diffusa or Oldenlandia (Sprending Hydyotis) for cancer Patients p179-192,) Springer Dordrecht Heidelberg London New York 2011.3.


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