(1)新型眼用纳米给药系统的研究；
(2)口服缓控释；
(3)改良型新药的研究。

1．科研项目
（1）国家自然科学基金：基于连接臂和肠转运器PepT1靶向的齐墩果酸口服前药研究（81001413/H3008），21万，已结题；
（2）国家自然科学基金：多功能有机/无机杂化纳米粒眼用给药系统的研究（81373362），65万，已结题；
（3）创新药羧胺三唑固体制剂的研究（校合2020-药167），100万，进行中；
（4）一类创新药环维黄杨星D及其盐酸盐的新剂型研究（校合2021-药280），100万，进行中；
（5）胰岛素口服液制剂的研究（校合2021-药244），50万，进行中；
（6）基于新疆医药资源的创新药物开发关键技术研究，100万，进行中；
（7）交联玻璃酸钠及其注射剂研发咨询服务，300万，进行中。

1.Lu JH,Zhu XM,Zhang M,Jiang XC,Guo W(共同通讯作者),Jiang F(共同通讯作者),Cao F(操锋，通讯作者). In vitro and in vivo assessment of structural integrity for HPCD complex@Liposome nanocomposites from ocular surface to the posterior segment of the eye. Carbohydr Polym. 2023,315:120960.(IF：11.2)
2.Li XL，Jiang XC，Zhou XL, Cheng YJ(共同通讯作者), Cao F(操锋，通讯作者). Development of dexamethasone suspension eye drops: A comparative investigation of ternary and quaternary cyclodextrin aggregates. J Drug Deliv Sci Tec, 2023, 82: 104383.(IF：5.06)
3.Sun LP,Zhang M,Shi Y,Fang L(共同通讯作者), Cao F(操锋，通讯作者).Rational design of mixed nanomicelle eye drops with structural integrity investigation. Acta Biomater.2022,141:164-177.(IF：10.63)
4.Zhou XY,Li XL, Xu JM, Cheng YJ(共同通讯作者), Cao F(操锋，通讯作者).Latanoprost-loaded cyclodextrin microaggregate suspension eye drops for enhanced bioavailability and stability.Eur J Pharm Sci. 2021,160,105758.(IF：5.112)
5.Xu C, Lu JH, Zhou L, Liang J, Fang L(共同通讯作者), Cao F(操锋，通讯作者). Multifunctional nanocomposite eye drops of cyclodextrin complex@layered double hydroxides for relay drug delivery to the posterior segment of the eye. Carbohydr Polym. 2021,260:117800.(IF：9.381)
6.Wang Y, Zhou L, Fang L(共同通讯作者), Cao F(操锋，通讯作者). Multifunctional carboxymethyl chitosan derivatives-layered double hydroxides hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye. Acta Biomater. 2020,104:104-114.(IF:7.242)
7.Xu X, Sun L, Zhou L, Cheng Y(共同通讯作者), Cao F(操锋，通讯作者).Functional chitosan oligosaccharide nanomicelles for topical ocular drug delivery of dexamethasone.Carbohydr Polym. 2020,227:115356.(IF:7.182)
8.Gu Y, Xu C, Wang Y, Zhou X, Fang L(共同通讯作者), Cao F(操锋，通讯作者). Multifunctional nanocomposites based on liposomes and layered double hydroxides conjugated with glycylsarcosine for efficient topical drug delivery to the posterior segment of the eye. Mol Pharm. 2019，16(7):2845-2857.(IF：4.39)
9.Wang Y, Xu X, Gu Y, Cheng Y(共同通讯作者), Cao F(操锋，通讯作者). Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye. Expert Opin Drug Deliv. 2018,15(7):687-701.(IF：5.6)
10.Xu TT, Zhang J, Chi HB, Cao F(操锋，通讯作者). Multifunctional properties of organic-inorganic hybrid nanocomposites based on chitosan derivatives and layered double hydroxides for ocular drug delivery. Acta Biomaterialia. 2016, 36:152-63. (IF: 6.025)