2008年毕业于郑州大学,获理学学士学位;2014年毕业于中国科学院大学(中国科学院生物物理研究所),获理学博士学位。随后在上海科技大学从事博士后研究,2017年赴康奈尔医学院、霍华德·休斯医学研究所开展研究工作,先后担任博士后、研究专家。2026年加入中国药科大学药学院。长期从事膜蛋白分子机制及其在生理和病理中的作用研究,揭示了SatP识别与通透乙酸的分子机制,以及多种离子和小分子调控人源谷氨酸转运体功能的分子机制。相关工作以第一作者或通讯作者(含共同)发表于 Science Advances、Nature Communications、PNAS、EMBO Journal、Cell Research 等期刊。
药学院招生学科:药理学,药学-新药临床前评价
1. P. Koochaki#, B. Qiu#, J. A. Coker#, A. Earsley, N. S. Wang, T. Romigh, C. M. Goins, S. R. Stauffer*, O. Boudker*, A. A. Chakraborty*, Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism. EMBO J (2026). https://doi.org/10.1038/s44318-026-00776-2
2. B. Qiu, O. Boudker*, Structural basis of excitatory amino acid transporter 3 substrate recognition. Proc. Natl. Acad. Sci. U.S.A. 122 (16) e2501627122, https://doi.org/10.1073/pnas.2501627122 (2025).
3. B. Qiu*, O. Boudker*, Symport and antiport mechanisms of human glutamate transporters. Nature Communications 14, 2579 (2023).
4. B. Qiu, D. Matthies, E. Fortea, Z. Yu, O. Boudker*, Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport. Sci Adv 7 (2021).
5. Y. Jiang, A. Miyagi, X. Wang, B. Qiu, O. Boudker, S. Scheuring*, HS-AFM single-molecular structural biology uncovers basis of transporter wanderlust kinetics. Nature Structural & Molecular Biology 31, (8) 1286-1295 (2024)
6. Y. Huang*, K. Reddy, C. Bracken, B. Qiu, W. Zhan, D. Eliezer*, O. Boudker*, An environmentally ultrasensitive fluorine probe to resolve protein 19F NMR probe for monitoring protein conformational by 19F-NMR and cryo-EM. J Am Chem Soc 145 (15): 8583-8592 (2023)
7. B. Qiu#, B. Xia#. Zhou, Y. Lu, M. He, K. Hasegawa, Z. Ma, F. Zhang, L. Gu, Q. Mao, F. Wang, S. Zhao, Z. Gao*, J. Liao*, Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate. Cell Res 28 (6), 644-654 (2018).
8. B. Qiu, K. Zhang, S. Wang, F. Sun*, C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation. Biochem Biophys Res Commun 446, (1) 380-386 (2014).
# 同等贡献, * 通讯作者


