胡庆华，药理学教授，博士生导师，现任中国药科大学研究生院副院长、“转化药理学”校企联合实验室主任。中国药理学会心血管药理专业委员会第二届青委会副主任委员，第十三届全国大学生创新创业年会优秀指导教师，江苏省“青蓝工程”中青年学术带头人。研究方向为免疫炎症疾病治疗靶标发现和新药研发，先后主持3项国家自然科学基金、1项江苏省自然科学基金和多项企事业横向合作课题。近年来在J Adv Res、Drug Discov Today、Cell Death Dis、Front Immunol、J Med Chem等期刊发表论文50余篇；申请发明专利8项，授权4项，完成专利成果转化1项；获江苏省教育成果奖二等奖1项，全国研究生规划教材《医药知识产权》副主编，全国本科生规划教材《药理学》、《药物毒理学》编委，Signal Transduct Tar、Br J Pharmacol、J Med Chem等杂志审稿人。
联系方式：huqh@cpu.edu.cn，025-86185970，江宁校区学院实验楼408。
近3年部分代表作：
1. Liu CX, Zhou MZ, Jiang WJ, Ye SM, Tian S, Jiang C, Hao K, Li HQ, Hu QH*. GPR105-Targeted therapy promotes gout resolution as a switch between NETosis and apoptosis of neutrophils. Front Immunol 13: 870183 (2022).
2. Li HW, Jiang WJ, Ye SM, Zhou MZ, Liu CX, Hao K, Hu QH*. P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages. Cell Death Dis 11: 394 (2020).
3. Wang WW, Liu CX, Li HW, Tian S, Liu Y, Wang NX, Yan D, Li HQ, Hu QH*. Discovery of novel and potent P2Y14R antagonists via structure-based virtual screening for the treatment of acute gouty arthritis. J Adv Res 23: 133-142 (2020).
4. Zhou MZ, Wang WW, Li YH, Zhang Q, Ji H, Li HQ, Hu QH*. The role of P2Y6R in cardiovascular diseases and recent development of P2Y6R antagonists. Drug Discov Today 25: 568-573 (2020).
5. Hao K, Jiang WJ, Zhou MZ, Li HW, Chen YD, Jiang F, Hu QH*. Targeting BRD4 prevents acute gouty arthritis by regulating pyroptosis. Int J Biol Sci 16: 3163-3173 (2020).
6. Ye SM, Zhou MZ, Jiang WJ, Liu CX, Zhou ZW, Sun MJ, Hu QH*. Silencing of Gasdermin D by siRNA-Loaded PEI-Chol lipopolymers potently relieves acute gouty arthritis through inhibiting pyroptosis. Mol Pharm 18: 667-678 (2021).
7. Lu R, Wang YL, Liu CX, Zhang ZG, Li BY, Meng ZB, Jiang C, Hu QH*. Design, synthesis and evaluation of 3-amide-5-aryl benzoic acid derivatives as novel P2Y14R antagonists with potential high efficiency against acute gouty arthritis. Eur J Med Chem 216: 113313 (2021).
8. Yang XP, Zhi JK, Leng HF, Chen Y, Gao HR, Ma JM, Ji J, Hu QH*. The piperine derivative HJ105 inhibits Aβ 1-42-induced neuroinflammation and oxidative damage via the Keap1-Nrf2-TXNIP axis. Phytomedicine 87: 153571 (2021).
9. Hou SH, Yang XP, Yang YJ, Tong Y, Chen QW, Wan BH, Wei R, Lu T, Chen YD, Hu QH*. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. Eur J Med Chem 220:113482 (2021).
10. Yang XP, Ji J, Liu CX, Zhou MZ, Li HW, Ye SM, Hu QH*. HJ22, a Novel derivative of piperine, attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2. Int Immunopharmacol 83: 106383 (2020).
