(1) 正离子催化
(2) 主族元素化学
(3) 药物化学

1）基于弱配位抗衡阴离子稳定的芳基正离子和硅正离子，发展了一系列正离子催化新策略和新方法，实现了全烷基取代硅烷的催化可控循环升级、非活化卤代芳烃的亲电取代以及基于β-硅效应的催化硅化等。
2）基于铑催化策略，发展了一系列催化硅化新方法。

1) He, T.; Klare, H. F. T.; Oestreich, M. Arenium-ion-catalysed halodealkylation of fully alkylated silanes. Nature 2023, 623, 538-543. (IF = 64.8, 2022)
2) He, T.; Klare, H. F. T.; Oestreich, M. Catalytically generated Meerwein's salt-type oxonium ions for Friedel–Crafts C(sp2)–H methylation with methanol. J. Am. Chem. Soc. 2023, 145, 3795-3801. (IF = 15.0, 2022)
3) He, T.; Klare, H. F. T.; Oestreich, M. Perdeuteration of deactivated aryl halides by H/D exchange under superelectrophile catalysis. J. Am. Chem. Soc. 2022, 144, 4734-4738. (IF = 15.0)
4) He, T.; Qu, Z.-W.; Klare, H. F. T.; Grimme, S.; Oestreich, M. Intermolecular carbosilylation of α-olefins with C(sp3)‒C(sp) bond formation involving silylium-ion regeneration. Angew. Chem. Int. Ed. 2022, 61, e202203347. (IF = 16.6)
5) He, T.; Wang, G.; Bonetti, V.; Klare, H. F. T.; Oestreich, M. Silylium-ion-promoted (5+1) cycloaddition of aryl-Substituted vinylcyclopropanes and hydrosilanes involving aryl migration. Angew. Chem. Int. Ed. 2020, 59, 12186-12191. (IF = 15.3)
6) He, T.; Liu, L.; Guo, L.; Li, B.; Zhang, Q.-W.; He, W. Rhodium catalyzed intermolecular trans-disilylation of alkynones with unactivated disilanes. Angew. Chem. Int. Ed. 2018, 57, 10868-10872. (IF = 12.2)
7) He, T., Bin Li†, Lichuan Liu, Wenpeng Ma, Wei He*. Rhodium-catalyzed intermolecular silylation of C(sp)-H by silacyclobutanes. Chem. Eur. J. 2021, 27, 5648-5652. (equal contribution) (IF = 5.02)
8) He, T.; Liu, L.; Ma, W.; Li, B.; Zhang, Q.-W.; He, W. Enantioselective construction of Si‐stereogenic center via rhodium‐catalyzed intermolecular hydrosilylation of alkene. Chem. Eur. J. 2020, 26, 17011-17015. (IF = 5.23)
9) He, T.; Li, B.; Liu, L.; Wang, J.; Ma, W.; Zhang, Q.-W.; He, W. Copper-catalyzed trifunctionalization of alkynes: rapid assembly of oxindoles bearing geminal diboron. Chem. Eur. J. 2019, 25, 966-970. (IF = 4.85)
10) Xu, Y.-H.; He, T.; Zhang, Q.; Loh, T.-P. Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)2 with molecular oxygen as an oxidant. Chem. Commun. 2014, 50, 2784-2786. (equal contribution) (IF = 6.83)
11) Long, P.-W.; He, T.; Klare, H. F. T.; Oestreich, M. Skeletal Rearrangements Involving Cyclopropyl- and Alkene-Stabilized Silylium Ions. Synlett 2023, doi: 10.1055/a-2188-1842. (Account) (equal contribution) (IF = 2.0)